General Healthcare

6 Traditional and Science Proven Joint Pain Relief

Traditional and Science Proven Joint Pain Relief

Traditional and Science Proven Joint Pain Relief

Any portion of a joint, including cartilage, bone, ligaments, tendons, or muscles, can cause joint pain, which can manifest as discomfort, pain, or inflammation. However, the most typical definition of joint pain is arthritis or arthralgia, which is pain or inflammation within the joint itself. This article focuses on traditional and science proven joint pain relief and how you are able to minimize or completely remove the pain.

1. Paracetamol

All age groups and many arthritic disorders respond well to paracetamol. It is generally well tolerated in osteoarthritis patients for up to 12 months and has been suggested as the oral analgesic of choice for mild to moderate pain. Although recent reports have linked frequent use of paracetamol to a slight rise in the risk of incident hypertension, paracetamol generally has an excellent tolerability profile and overall safety record.

*Osteoarthritis occurs when the protective cartilage that cushions the ends of the bones wears down over time. Although osteoarthritis can damage any joint, the disorder most commonly affects joints in your hands, knees, hips and spine.

2. Tramadol

The central-acting oral analgesic tramadol has a special dual mode of action that inhibits the reuptake of noradrenaline and serotonin while also functioning as a mild agonist. It is widely accepted for use in treating both moderate and severe pain, and it is also effective as an adjuvant therapy for joint pain. Tramadol and paracetamol work well together, allowing for a reduction in NSAID use without sacrificing analgesia. Due to toxicity, the drug’s use is restricted in a sizeable fraction of patients. The most often reported adverse effects include nausea, dizziness, and constipation. Because of the potential elevation of basal serotonin levels and associated risks of seizures, caution should be used when using serotonin-selective reuptake inhibitors concurrently.

3. Non-steroidal anti-inflammatory drugs

NSAIDs continue to be one of the main pharmacological treatments for joint pain due to their demonstrated significant efficacy in the treatment of acute pain. The relative merits of NSAIDs over paracetamol as first-line analgesic therapy for arthritic diseases. NSAIDs are superior to paracetamol for treating knee and hip pain in osteoarthritis, according to a recent meta-analysis of 15 RCTs including 5,986 participants. However, the effect sizes for both therapies were rather small. NSAIDs are also frequently used as part of rheumatoid arthritis symptomatic therapy, but only small effects are seen.

*Rheumatoid arthritis is an autoimmune and inflammatory condition in which your immune system unintentionally assaults healthy cells in your body, leading to inflammation (painful swelling) in the areas of your body affected. RA primarily targets joints, typically a number of joints at once.

Gastrointestinal events, such as perforation, ulceration, and bleeding, are some of the side effects of NSAIDs. However Oedema and renal insufficiency are two additional issues that are well known.

4. Opioids

Stronger opioids used over an extended period of time to treat chronic musculoskeletal disorders are still debatable. Oxycodone (OxyContin), hydrocodone (Vicodin), morphine, and methadone are examples of common kinds. A synthetic opioid painkiller is fentanyl. The data supporting the solitary use of weaker opioids like codeine for chronic arthritic pain is rather scant, but these medications have no major organ-damaging side effects and may be clinically safe for long-term therapy when taken with paracetamol. the most commonly reported opioid side effects are constipation, nausea and somnolence.

Traditional Joint Pain Treatment

Traditional Joint Pain Treatment

1. Acupuncture

Acupuncture is a common supplemental or alternative treatment that patients with arthritis pain turn to for relief. A few systematic reviews offered generally positive support with symptomatic improvements over both sham acupuncture and placebo. With few reports of major side effects overall, acupuncture has a strong safety record and continues to be used in the symptomatic treatment of arthritis patients.

2. Electrical nerve stimulation

Although there have been few studies evaluating the technique’s effectiveness for arthritic pain, electrical nerve stimulation has a well-established general role in the treatment of chronic pain. Although the exact mechanisms of action are still unknown, TENS has been shown to reduce spinal stimulatory neurotransmitters (glutamate and aspartate) while simultaneously activating modulatory opioid, serotonin, and/or muscarinic receptors to alleviate pain behaviors in studies of experimental joint inflammation [46]. TENS has been shown in clinical tests to be as beneficial as exercise and superior than placebo in managing arthritic pain, however combined techniques yield the best results.

best supplement for joint pain

Glucosamine and Chondroitin  

Two of the most popular dietary supplements for arthritis are glucosamine and chondroitin. They are a part of the cartilage, which cushions the joints.

According to a study, individuals with knee osteoarthritis were given either glucosamine and chondroitin alone or in combination with an NSAID and a placebo (OA), Symptoms like pain and function were improved by glucosamine, although it wasn’t substantially better than a placebo. However, a 2016 multinational trial discovered that the combination was just as effective at lowering pain, stiffness, and swelling in knee OA as the NSAID celecoxib.

The most effective type of the supplements has also been the subject of varying studies. According to certain data, glucosamine sulphate is the best. For some people, glucosamine hydrochloride works better. One study that directly evaluated the two treatments found that they both provided comparable pain alleviation.

Fish Oil

Fish contains polyunsaturated omega-3 fatty acids, which have strong anti-inflammatory effects. Omega-3 fatty acids appear to be more effective for treating rheumatoid arthritis than osteoarthritis, most likely because inflammation is the primary cause of rheumatoid arthritis.

Omega-3 supplements were reported to lessen RA-related joint discomfort, stiffness, and swelling. Some people may be able to reduce their need of painkillers while also avoiding their adverse effects by taking these supplements. It could be preferable to turn to vitamins rather than ibuprofen for mild cases of arthritis. Omega-3s also have the added benefit of preventing dementia and heart disease.

Omega-3s are also present in plant-based sources like flax and chia seeds, however they are present as short-chain alpha-linolenic acid (ALA). The majority of the health advantages are provided by the long-chain omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Make sure the EPA and DHA content is listed when you purchase fish oil, and make sure you consume at least one gram of EPA and DHA daily. Omega-3 supplements made from algae are an option for vegans.


The body naturally produces S-adenosyl-methionine (SAM-e), which has anti-inflammatory, cartilage-protecting, and pain-relieving properties. In tests, it was comparable to NSAIDs like ibuprofen and celecoxib in terms of OA pain relief while having none of their negative side effects.

There is an added plus with SAM-e. Since the supplement has a modest to moderate antidepressant effect, it is most helpful if you also suffer depression. The usual daily dosage of SAM-e is 1,200 mg. It will take a few weeks before you get the full results of this vitamin.


The active ingredient of turmeric, a spice with a yellow tint and a common ingredient in Indian curries, is curcumin. It functions as a potent anti-inflammatory agent in the body, inhibiting the same enzyme that celecoxib, a COX-2 inhibitor, uses to cause inflammation.

A 1,500 mg daily dose of curcumin extract was just as beneficial as a 1,200 mg daily dose of ibuprofen in a study of 367 individuals with knee OA, without the gastrointestinal side effects. Additionally, this supplement seems to reduce RA discomfort and swelling.

Curcumin has a drawback in that it is challenging for the body to absorb. It should be consumed along with a source of fat. It’s crucial that some of the nutrients are in an oil base.

How can I naturally lubricate my joints?

Consuming good fats can improve the lubrication and health of your joints. Salmon, trout, mackerel, avocados, olive oil, almonds, walnuts, and chia seeds are among the foods high in beneficial fats. These meals’ omega-3 fatty acids will help with joint lubrication.

Because exercise raises the water content of your synovial fluid and lubricates your joints, it can significantly relieve pain. During exercise, the synovial fluid is also distributed uniformly because joint movement forces the fluid to get to areas of the joints where it might not typically go.

As water increases synovial fluid volume and enables the fluid to evenly surround the joint, it can also help to lubricate joints. Ensure that you are getting the recommended amount of water for your needs and way of life.

**Special credit to National Library of Medicine and Arthritis Foundation**

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